Unfortunately, there is no conclusive answer I can provide.

Sometimes, powerline adapters will work across multiple circuit breakers and sometimes they will not. If they do, they will likely have decreased speed.

I can though tell you that I did setup a network in one person's home that it did work.
In the situation, the modem and router were in the living room. From there, a set of powerline adapters was used to bring connection to upstairs bedrooms as well as another in a guest house on separate breaker. In both cases, lines were run from powerline adapters to access points to provide wifi across entire property.